Researchers Discover Gene Responsible For Pain Insensitivity
Researchers have discovered a third gene, which is associated with pain detection in human body, whose mutation is the major cause behind people’s inherited insensitivity to feel any pain.
Scientific endeavors behind figuring out the sources of pain are very important for one million people who suffer from Congenital insensitivity to pain (CIP) disorder. Unlike majority of the people, pain for these people is a blessing. Just by logically thinking, we realize that pain and pleasure indicate what should be avoided or adopted. Thus, we avoid those acts that inflict pain on us.
However, people who are insensitive to pain will not know any injuries or diseases and, thus, go untreated. The aftermath of letting the diseases spread or injuries expand can be as bad as an early death.
According to the researchers, people lose their ability to sense pain when both copies of the gene PRDM12 are mutated. The condition is accompanied by absence of pain-sensing neurons, they add.
“The ability to sense pain is essential to our self-preservation, yet we understand far more about excessive pain than we do about lack of pain perception. Both are equally important to the development of new pain treatments — if we know the mechanisms that underlie pain sensation, we can then potentially control and reduce unnecessary pain,” said Geoff Woods of the University of Cambridge
The new findings, as observed by The Guardian, can pave the way for more deeper analysis of pain phenomena. This can lead the medical experts to develop treatment strategies for CIP sufferers. Equally important will be the alleviation of pain, by slowing down the PRDM12, for those who can feel it.